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Falecalcitriol Outcome of COX overexpression Although a cau
2019-09-09
Outcome of COX-2 overexpression Although a causal role for COX-2 has been proposed, mechanisms by which COX-2 function contributes to the pathogenesis of hyperplastic disease are not well defined.
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Abbreviations Introduction Collagen induced DDR activation
2019-09-07
Abbreviations Introduction Collagen-induced DDR activation A key feature of DDRs is their ability to bind both fibrillar and non-fibrillar collagens (Shrivastava et al, 1997, Vogel et al., 1997).
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Park et al expanded their own
2019-09-06
Park et al. [34] expanded their own model as hydrogen- bonding lattice fluid EOS (NLF-HB) [35] for calculating the activity coefficients of aqueous amino Dronedarone solution. Further, Pazuki et al. [36] extended the perturbed hard chain theory which has been proposed by Beret and Prausnitz [37] for modeling the solute activity coefficient and solubility of aqueous amino acid solutions.
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The current study demonstrates a link between
2019-09-05
The current study demonstrates a link between heme metabolism and mitochondrial Co-I, which deficits instigate abnormalities in the metabolism of heme and its downstream targets both in-vitro in patients and healthy subjects derived LCLs and in-vivo in brains of SZ-rat model.
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A more refined picture of cholinesterase activity patterns m
2019-09-04
A more refined picture of cholinesterase activity patterns may be obtained by measuring ChE activity of the same sample before and after addition of certain cholinesterase inhibitors, with differential specificity for different components of total ChE activity, such as BW284c51 (BW1,5-bis-(4-allyldimethylammoniumphenyl) pentan-3-one dibromide = a specific AChE inhibitor), isotetramonoisopropyl pyrophosphortetramide (iso-OMPA = a specific BChE inhibitor in vertebrates) and eserine (physostigmine, or (1’methylpyrrolidino (2’:3’:2:3)1,3-dimethylindolin-5-yl N-methylcarbamate = a total cholinesterase inhibitor).
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In this report we evaluate if this
2019-09-03
In this report, we evaluate if this molecular mechanism is used universally by high-fidelity DNA polymerases during the replication of DNA lesions that are structurally distinct from abasic sites.
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The following are the supplementary
2019-09-02
The following are the supplementary data related to this article. Acknowledgments Introduction Drug-resistant epilepsy (DRE) occurs in approximate 30% of patients who suffer from epilepsy [1].
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We used two different VSMCs cell lines KSB
2019-08-30
We used two different VSMCs cell lines, KSB and CSD (isolated from two different thoracic aortas). Rat aortic VSMCs were isolated from medial segments from thoracic rate Cariprazine from Wistar-Kyoto rats (six to eight weeks old, Charles River Wiga GmbH) and cultured over several passages as described .
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Neonatal hydronephrosis induced by TCDD exposure via lactati
2019-08-29
Neonatal hydronephrosis induced by TCDD exposure via lactation has a critical window for onset: the incidence of this disease peaks around PNDs 1–4, followed by a rapid decrease to a substantially null level in adulthood (Couture-Haws et al., 1991; Yoshioka et al., 2016).
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As DAPK is dependent on Ca
2019-08-28
As DAPK1 is dependent on Ca2+/CaM for its activity, its role in induction of autophagy is Ca2+-dependent and will be described in Section 5.1. LRRK1 and 2 were however shown to regulate autophagy in numerous studies where the role of Ca2+ was not investigated, and these mechanisms will be described here below.
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Exogenous administration of POCs could
2019-08-27
Exogenous administration of POCs could theoretically inhibit breastfeeding [69]; however, the evidence in this review does not generally support a negative impact on breastfeeding outcomes.
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Western blotting Western blotting was performed following th
2019-08-26
Western blotting: Western blotting was performed following the standard protocol as previously described [16]. All the images were collected using the Odyssey Fc imaging system (Li-COR Biosciences).
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Two primary members of the TRIM family TRIM and
2019-08-24
Two primary members of the TRIM family – TRIM5α and TRIM25 – function as antiviral effector and immune regulator, respectively.
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Alvespimycin Meanwhile high levels of extraversion
2019-08-23
Meanwhile, high levels of extraversion have been associated with weaker conditioning and faster Alvespimycin learning (Eysenck, 1970).
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E intracellular localization Regulation of E by
2019-08-22
E1 intracellular localization Regulation of E1 by other post-translational modifications Concluding remarks
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