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The distorted geography on the number lines of many
2019-12-29
The distorted geography on the number lines of many pre-service primary teachers in this study also highlights the need to provide them with strong visual models of negative numbers and their ordering. The evidence from Indri\'s interview is that some standard models of negative numbers (e.g., lend
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Due to its several industrial applications the recombinant p
2019-12-29
Due to its several industrial applications, the recombinant production of collagen and all its derivatives as gelatins has been pursued for many years in different biological systems as mammalian Boc-D-FMK (Toman et al., 1999), tobacco plants (Ruggiero et al., 2000), silkworms (Tomita et al., 2003)
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br Nuclear export and the functions of CRM
2019-12-29
Nuclear export and the functions of CRM1 The nuclear envelope provides a compartmentalized intracellular environment for DNA replication, the synthesis of RNA, and production of ribosomes, and, as such, it can regulate cellular biological processes including apoptosis and proliferation. Nucleocyt
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Of all the residues of plants the ash obtained
2019-12-29
Of all the residues of plants, the ash obtained from the incineration of RH has highest amount of silica content [7]. The rice crop normally ingest orthosilicic meclofenamate in large quantity from ground water and this acid is further polymerized in the husk, ultimately contribute to amorphous sil
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Some pyrimidine analogs are substrate
2019-12-28
Some pyrimidine analogs are substrate-based inhibitors that bind to the dihydroorotate binding site, but most reported inhibitors of DHODH bind to the site occupied by the ubiquinone co-factor., , , , , , , , , , , , , , , , , X-ray crystallographic studies of inhibitor complexes with DHODH and DHOD
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concerning The lungs dissected from week mice were cut into
2019-12-28
The lungs dissected from 4–5-week mice were cut into small pieces and then immersed in Dulbecco\'s modified Eagle\'s medium (Invitrogen, Carlsbad, CA) containing collagenase II (2 mg/ml), trypsin (2.5 mg/ml), Dnase I (2 mg/ml), penicillin (100 U/ml), and streptomycin (100 μg/ml) for 12 hours at 37
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Xenobiotic metabolism primarily occurs in liver which contai
2019-12-28
Xenobiotic metabolism primarily occurs in liver, which contains many enzymes to catalyze the transformation of xenobiotic. Usually, cytochrome P-450s (CYP450s) act as the first response for biotransformation of xenobiotic in organisms. CYP450s generally consist of various subfamily enzymes which can
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br Use of CDK inhibitors
2019-12-28
Use of CDK inhibitors in CLL today There has been explosive development of novel therapeutics for CLL in the last decade and a massive transformation of practice is underway [75]. Most of this development and excitement revolves around B-cell receptor (BCR) signaling inhibitors: the Bruton tyrosi
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In the last and the most
2019-12-28
In the last and the most challenging part, three mixtures were selected to evaluate the reliability of the presented correlation and the CPA model. For Athabasca bitumen, Amani et al. [25] measured the experimental data at very high temperatures compared to the thermal recovery range up to 644 K (ne
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br Tests and measurements We used a set of
2019-12-28
Tests and measurements We used a set of FPGA cores for all tests and measurements. Firstly, the control circuit for the Controlled Current Limiter illustrates the proposed TMR method. The circuit contains a D-Register to enable or disable the power to the protected device, a counter, which is us
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br Acknowledgments br Casein kinases CK are serine threonine
2019-12-28
Acknowledgments Casein kinases (CK) are serine/threonine-specific enzymes and can be divided two subtypes: casein kinase 1 (CK1) and casein kinase 2 (CK2). CK1 contains at least seven isoforms (α, β, γ1, γ2, γ3, δ and ε) expressed in eukaryotic organisms, CK1 is involved in various cellular pro
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br Roles for intracellular chloride channels br Specific chl
2019-12-28
Roles for intracellular chloride channels Specific chloride channel proteins in intracellular membranes Concluding remarks Introduction The sulfonylurea derivative glybenclamide (GLYB) is used as oral hypoglycemic agent to treat non-insulin dependent diabetes mellitus [1], [2]. The antid
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Sumatriptan mg br Materials and methods br Results br Discus
2019-12-28
Materials and methods Results Discussion For many years, oral PDE5-Is have been prescribed as an on-demand regimen for treating ED. Several studies have reported on the efficacy and safety of such a regimen, with an overall efficacy rate of 60–70% [21]. However, many patients complain of a
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br Effects of estrogens on bone Estrogens
2019-12-28
Effects of estrogens on bone Estrogens play an important role in bone remodeling, as demonstrated by studies in mice in which the ER genes were deleted [21], [22]. ERβ compensates for the L-745,870 trihydrochloride of ERα, and vice versa, but when both ERs are deleted a profound decrease in trab
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br Target enzyme attributes and substrate peptide selection
2019-12-28
Target enzyme attributes and substrate peptide selection Protein kinases catalyze the phosphorylation of serine, threonine, and tyrosine residues in both proteins and peptides using ATP as the phosphoryl donor. The human kinome is comprised of 518 protein kinases and 40 lipid kinases. The vast ma
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