• survivin (baculoviral IAP repeat-containing protein 5) (21-2

  2021-05-20

  

  Molecular imaging that provides a non-invasive means to visualize and measure a biological process of interest at the molecular and cellular level in living subjects has emerged as a promising approach for in vivo detection of enzyme activity in recent decades [6]. In survivin (baculoviral IAP repea

• Neuronal cells have highly developed ER which

  2021-05-20

  

  Neuronal glucokinase inhibitor have highly developed ER, which makes them susceptible to loss of ER function following exposure to various agents, which leads to apoptosis (Lindholm et al., 2006, Katayama et al., 2004). Multiple pathways may be involved in ER stress-initiated apoptosis. Among them,

• In vitro studies in NSCLC cell lines expressing EGFR mutants

  2021-05-20

  

  In vitro studies in NSCLC cell lines expressing EGFR mutants (T790M mutation, exon 19 deletion E746-A750, L858R/T790M double mutation), demonstrated that Rociletinib potently inhibits proliferation in the mutant EGFR NSCLC dna-pk inhibitor with Growth inhibition (GI50) values ranging from 7 to 32 n

• br Asb Proteins and Mitochondrial Function

  2021-05-20

  

  Asb Proteins and Mitochondrial Function Mitochondria are intracellular organelles in eukaryotic erk definition and are the main sites of oxidative phosphorylation and ATP production. In addition, mitochondria serve as signal transduction docking stations in pyroptosis and regulate a plethora of

• br Conflicts of interest br Acknowledgements

  2021-05-20

  

  Conflicts of interest Acknowledgements Introduction Atherosclerosis is the number one cause of death in the United States and among the leading causes of morbidity and mortality globally [1]. Inflammation is critical in all stages of atherosclerosis from the formation of a plaque in the ves

• ABH expression is elevated in prostate carcinomas

  2021-05-20

  

  ABH3 expression is elevated in prostate carcinomas and has been referred to as prostate cancer antigen-1 or PCA-1. ABH3/PCA-1 was proposed as a diagnostic marker for prostate cancers, and suggested as a possible therapeutic target [82]. However, the recent studies of ABH2 and ABH3-null mice indicate

• In order to assess quantitatively the contribution of

  2021-05-19

  

  In order to assess quantitatively the contribution of the ung, dug and dut Flufenamic acid to uracil-DNA accumulation in E. coli, we have developed a novel method for measuring uracil residues in DNA that is based on the approach of Kow and co-workers [33] for measuring AP-sites in DNA. The method,

• Kuo et al Have shown that DAPK function

  2021-05-19

  

  Kuo et al. (2006) Have shown that DAPK1 function in inhibiting microtubule (MT) assembly is through the activation of microtubule affinity-regulating kinases (MARK)/PAR-1 family kinases MARK1/2, which destabilize MT by phosphorylating tau and related MAP2/4. This relation with DAPK1 has demonstrated

• br Materials and methods br Results br

  2021-05-19

  

  Materials and methods Results Discussion Taken together with our previous report, our current data demonstrate induction of Chk in monocytes by IL-3, IL-4, IL-13, and GM-CSF ((Musso et al., 1994) and Fig. 1, Fig. 2, Fig. 3, Fig. 4). Chk paroxetine hydrochloride is also inducible by stem ce

• br Introduction Concrete is one

  2021-05-19

  

  Introduction Concrete is one of the most commonly used materials in the construction industry and its raw material is available throughout the world. Concrete is derived from ordinary Portland cement and is used for the construction and development of infrastructures. Research shows that demand f

• The interferences between thapsigargin and

  2021-05-19

  

  The interferences between thapsigargin- and forskolin-induced Ca release indicate that these drugs deplete the same intracellular stores in RASMC. In fact, after partial depletion of thapsigargin-sensitive stores, the forskolin-induced increases in [Ca]c were significantly reduced. Similarly, a prev

• br The contribution of Interference RNA and epigenetic

  2021-05-19

  

  The contribution of Interference RNA and epigenetic in OA attenuation Interference RNA, a cellular mechanism for post-transcriptional gene silencing that is associated with mRNA. The potential of RNAi has successfully silenced the wide range of protein coding genes. Its high specificity sanctions

• In addition to playing important roles in the immune system

  2021-05-19

  

  In addition to playing important roles in the immune system, EBI2 is also expressed in the Cy5 carboxylic acid (non-sulfonated) synthesis of the central nervous system (CNS), namely astrocytes, and this receptor regulates astrocyte signalling, as well as astrocyte cell migration (Rutkowska et al.,

• It is reported that sympathetic nerve activity is increased

  2021-05-19

  

  It is reported that sympathetic nerve activity is increased in the SHR strain compared with that in the WKY strain (Judy and Farrell, 1979, Lundin et al., 1984, Sugimura et al., 2008) and NA content is increased in the CB of the New Zealand strain of hypertensive rat compared with that in normotensi

• Beyond phosphorylation cancer cells may alter pyrimidine bio

  2021-05-18

  

  Beyond phosphorylation, cancer Acetazolamide mg may alter pyrimidine biosynthesis through the activation of the proto-oncogenic transcription factor MYC. MYC is a master regulator of many different pathways and has significant influence on the expression of nucleotide metabolism genes. Previous stu

14166 records 619/945 page Previous Next First page 上5页 616617618619620 下5页 Last page